For all the talk of how dynamic San Francisco's offense could look with Christian McCaffrey and Deebo Samuel, it was the 49ers defense that once again led the way. McCaffrey ran for the go-ahead touchdown with 7:54 to play, and the Niners pitched a second-half shutout to beat the Los Angeles Chargers 22-16 Sunday night in their first game back from a bye week. read https://www.cbssports.com/nfl/gametracker/recap/NFL_20221113_LAC@SF/