Floyd Mayweather is arguably the best defensive fighter in boxing right now. But should a fight between him and Manny Pacquiao ever occur, there are several reasons as to why Pacquiao might give him fits in the ring. 1. STANCE. Manny Pacquiao is left-handed. Mayweather’s defense is tailored to fight orthodox fighters, not southpaws. Mayweather keeps his left hand low to protect the front of his body, and his right hand high to protect the right side of his head from orthodox left hooks. The only area he has exposed during this time is the left side of his body. But right-handed fighters generally have better left hooks than right hooks. This is simply because of the nature of their stance. Their right hand is held further back than their left, so when they lunge forward to throw a right hook, they have to extend further and expose much of themselves in the process. But Manny Pacquiao is a southpaw. He keeps his right hand in front of him, closer to his opponent, and throws better right hooks than left hooks. Mayweather has never fought someone who could throw excellent right hooks (in part because he has not fought any elite southpaw fighters), and because of this, he will find his defense severely compromised against Pacquiao. Read more: http://www.boxingnews24.com/2011/01/why-would-manny-pacquiao-give-floyd-mayweather-problems/