Even without its starting wide receivers, Oklahoma State had plenty left on offense. The Cowboys' big-play defense stepped up, too. Joseph Randle scored a career-best four touchdowns, two on runs that capitalized on an interception and fumble recovery by Shaun Lewis, as Oklahoma State (No. 4 BCS, No.6 AP) remained unbeaten and ended Missouri's 10-game home winning streak with a 45-24 victory on Saturday.