OT Coronavirus: America in chaos, News and Updates. One million Americans dead and counting

Discussion in 'Blazers OT Forum' started by SlyPokerDog, Jan 3, 2020.

  1. SlyPokerDog

    SlyPokerDog Woof! Staff Member Administrator

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    sfchronicle.com

    With coronavirus antibodies fading fast, vaccine hopes fade, too

    Disturbing new revelations that permanent immunity to the coronavirus may not be possible have jeopardized vaccine development and reinforced a decision by scientists at UCSF and affiliated laboratories to focus exclusively on treatments.

    Several recent studies conducted around the world indicate that the human body does not retain the antibodies that build up during infections, meaning there may be no lasting immunity to COVID-19 after people recover.

    Strong antibodies are also crucial in the development of vaccines. So molecular biologists fear the only way left to control the disease may be to treat the symptoms after people are infected to prevent the most debilitating effects, including inflammation, blood clots and death.

    “I just don’t see a vaccine coming anytime soon,” said Nevan Krogan, a molecular biologist and director of UCSF’s Quantitative Biosciences Institute, which works in partnership with 100 research laboratories. “People do have antibodies, but the antibodies are waning quickly.” And if antibodies diminish, “then there is a good chance the immunity from a vaccine would wane too.”

    The latest bad news came from scientists at King’s College of London, whose study of 90 COVID-19 patients in the United Kingdom found antibody levels peaked three weeks after the onset of symptoms and then dramatically declined.

    Potent antibodies were found in 60% of the patients, according to the study, but only 17% retained the same potency three months later. In some cases, the antibodies disappeared completely, said the study which was published as a preprint Saturday, meaning it has not yet been peer-reviewed.

    The report is the latest in a growing chain of evidence that immunity to COVID-19 is short-lived.

    A Chinese study published June 18 in the journal Nature Medicine also showed coronavirus antibodies taking a nosedive. The study of 74 patients, conducted by Chongqing Medical University, a branch of the Chinese Center for Disease Control and Prevention, showed that more than 90% exhibited sharp declines in the number of antibodies within two to three months after infection.

    There is still hope that the remaining antibodies will bestow some immunity, but infectious disease specialists around the world were surprised and discouraged by the rapid reduction observed in the studies. If the numbers continue dropping after three months, it could mean people will be susceptible to infection by the coronavirus year after year.

    https://www.sfchronicle.com/health/...rus-antibodies-fading-fast-focus-15414533.php
     
  2. barfo

    barfo triggered obsessive commie pinko boomer maniac Staff Member Global Moderator

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  3. barfo

    barfo triggered obsessive commie pinko boomer maniac Staff Member Global Moderator

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    Yeah, this is a major bummer.

    barfo
     
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  4. SlyPokerDog

    SlyPokerDog Woof! Staff Member Administrator

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    This sounds promising.

    Providence develops potential COVID-19 vaccine; wants feds to start human clinical trials

    Researchers at the Chiles Research Institute at Providence’s Robert Franz Cancer Center have asked the federal government for permission to start trials with humans.

    PORTLAND, Ore. — Scientists in Portland think they may have figured out a vaccine against COVID-19.

    Researchers at the Chiles Research Institute at Providence’s Robert Franz Cancer Center have asked the federal government for permission to start trials with human volunteers.

    They’re experts in cancer research and immunotherapy.

    Bernard Fox, Ph.D., and Rom Leidner, M.D. lead a team made up of several labs within the Institute.

    They want to use part of the virus’ structure against it.

    They believe those red spikes on the outside of the virus hold a key to building the body’s defenses.

    They want to inject volunteers with the DNA that makes just that part of the virus.

    “That DNA is taken up by your own cells and your own cells make those little spikes and secrete them or present them to the immune system as if you had the virus. Of course, you only have the little spikes you don’t have the virus. But the immune system gets to see that replica and get prepared,” said Dr. Leidner.

    Their plan also calls for a second injection of something called interleukin 12, which is a key part of our body’s response to viral infections. The injection gives the immune system a major boost, said Dr. Leidner.

    “And so it simulates, again as if you had the infection. We have a fake copy of the spike proteins that decorate the virus and we have this- the immune system's own ramping up signal to say ‘hey I’ve got an infection let’s get going and attack this’. The two together we think are an ideal combination,” he said.

    New drugs typically take a year and a half to bring to the public—but with a worldwide pandemic those timelines are speeding up dramatically.

    The researchers hope to get the green light to start with volunteers in the next month or two and if all goes well, have it ready for the rest of us by this time next year.

    https://www.kgw.com/article/news/he...d-19/283-53b2955e-4c3e-4e5d-8d9c-b71280861a31
     
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  5. SlyPokerDog

    SlyPokerDog Woof! Staff Member Administrator

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  6. Minstrel

    Minstrel Top Of The Pops Global Moderator

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    Americans Increasingly Dislike How Republican Governors Are Handling The Coronavirus Outbreak

    Throughout the coronavirus pandemic, governors have generally received better marks for the way they’ve handled the crisis than President Trump has. However, new polling suggests that may be changing, especially for Republican governors in states where the number of coronavirus cases has spiked in recent weeks.

    Gallup recently found that Americans in the 26 states governed by Republicans are souring on their leaders’ approach to the public health crisis, while sentiment remains steadily positive among residents of the 24 states governed by Democrats. In fact, over the past month, the share of respondents who agreed that their governor cared about the safety and health of their community fell by 8 points, from 61 percent to 53 percent, in states where a Republican is governor; opinion in Democratic-run states hovered around 65 percent, despite some movement week to week.

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    And on the question of how clearly governors were communicating their plans to address the coronavirus, the GOP also got low marks. Among respondents in Republican-run states, just 43 percent said their governor offered a clear plan, down from 54 percent about a month ago. Meanwhile, 58 percent of respondents in Democratic-run states said that their governor was communicating clearly, which was nearly identical to the share who said so in early June.

    Gallup isn’t the only pollster to find GOP leaders getting lower scores for the way they’re dealing with the coronavirus pandemic. Change Research’s polling of six battleground states found especially poor numbers for Republican governors in two states where the number of coronavirus cases surged in the first half of July: Florida and Arizona. In Change’s polling, 57 percent disapproved of Florida Gov. Ron DeSantis’s handling of the outbreak, and a whopping 71 percent disapproved of Arizona Gov. Doug Ducey’s response. Additional polling in Arizona and Florida second these findings. OH Predictive Insights found that opinion of Ducey’s approach went from a net positive in June (59 percent approved, 37 percent disapproved) to a net negative in July (35 percent approved, 63 percent disapproved). Likewise, surveys by CBS News/YouGov found 53 percent of Floridians said DeSantis was doing a somewhat or very bad job and 62 percent of Arizonans said the same of Ducey.

    Not every Republican governor’s pandemic-response ratings are underwater, however. Some, in fact, have sterling numbers. In late June, a survey from the University of New Hampshire found Gov. Chris Sununu had a 78 percent approval rating for his handling of the virus. Considering Sununu is up for reelection this November, his response could help him win another two years in office. Meanwhile, in Ohio, 77 percent of respondents in a late-June Quinnipiac University poll approved of Gov. Mike DeWine’s performance. And in Massachusetts, another late-June survey from Suffolk University found 81 percent approved of Gov. Charlie Baker’s handling of the outbreak.

    What these three governors have in common is the coronavirus hasn’t been surging in their states recently as much as it has in Arizona or Florida, but that doesn’t explain everything. Texas’s case rate has also shot up since late June, but Gov. Greg Abbott has gotten better marks than either DeSantis or Ducey. A CBS News/YouGov survey, for instance, found that public opinion was split as to how well he was handling the crisis: 50 percent said he was doing a good job and 50 percent said he was doing a bad job. And in another early-July survey from The Dallas Morning News/UT-Tyler, 49 percent approved of Abbott’s response while 40 percent disapproved (10 percent said they neither approved nor disapproved).

    Some Democratic governors have middling approval ratings, too. Change Research’s early-July survey found, for instance, that 56 percent approved of Wisconsin Gov. Tony Evers’s handling of the pandemic, while 55 percent approved of Michigan Gov. Gretchen Whitmer and Pennsylvania Gov. Tom Wolf’s responses. And just 51 percent approved of North Carolina Gov. Roy Cooper’s efforts. Wolf got some better numbers from a Monmouth University poll released earlier this week, in which 67 percent said he’d done a good job handling the coronavirus, but Cooper seems to be stuck around 50 percent. A late-June survey from East Carolina University found 53 percent approved of his response.

    But on the whole, Americans have a somewhat more favorable view of the way Democratic governors have handled the pandemic than the way Republican governors are responding. In late June, a consortium of universities conducted a poll of governors’ handling of the coronavirus across all 50 states and found that the median approval rating for Democratic governors was about 55 percent, compared to 49 percent for Republican governors. And some Democratic executives have sky-high numbers for how they’ve handled the pandemic. A late-June poll from Siena College gave New York Gov. Andrew Cuomo a 76 percent approval rating for his handling of the coronavirus, while a Garin Hart Yang Research Group survey found that 69 percent of Kentucky voters approved of Gov. Andy Beshear’s response.

    Of course, as president, Trump’s response to the coronavirus has continued to garner the most attention, but unfortunately for him, public opinion of his efforts has only worsened. About 58 percent now disapprove of his handling of the pandemic while just 38 percent approve, according to FiveThirtyEight’s coronavirus polling tracker.

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  7. SlyPokerDog

    SlyPokerDog Woof! Staff Member Administrator

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  8. SlyPokerDog

    SlyPokerDog Woof! Staff Member Administrator

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    Why isn't Christmas in Red? What has happened to Christmas? OMG, RONA HAS KILLED CHRISTMAS!
     
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  9. Lanny

    Lanny Original Season Ticket Holder "Mr. Big Shot"

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    Yes Stacey, the rude comment was needed.
     
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  10. ABM

    ABM Happily Married In Music City, USA!

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  11. ABM

    ABM Happily Married In Music City, USA!

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    [​IMG]
     
  12. theprunetang

    theprunetang Shaedon "Deadly Nightshade" Sharpe is HIM

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  13. CupWizier

    CupWizier Well-Known Member

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    Silly dog. It's obviously Obama and Bidens fault. They didn't warn trump about the impending pandemic 3.5 years out of office.
     
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  14. ABM

    ABM Happily Married In Music City, USA!

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    Well, then, don't. Ruff.
     
  15. CupWizier

    CupWizier Well-Known Member

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  16. ABM

    ABM Happily Married In Music City, USA!

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    Easy for you to say, yes.

    Tell me, what isn't fake news these days. People are gonna believe what they wanna believe. Simple as that.
     
  17. BigGameDamian

    BigGameDamian Well-Known Member

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  18. wizenheimer

    wizenheimer Well-Known Member

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    the data about limited immunity has been increasing as we get further into this pandemic. This article joins a long line of articles questioning if long term immunity to Covid is even possible

    this article certainly doesn't generate any optimism. At the same time, I wonder if it really generates that much pessimism

    now, it's entirely possible I'm talking out of my colon on this, but that article seems to place a potential Covid vaccine in the same category as flu shots. Antibodies from having the flu don't last long either; a matter of weeks IIRC. People can get the flu 2 or even 3 times in a bad flu season if they don't get the vaccine. The antibodies from a flu vaccine significantly increase the anti-body resistance time over that of a flu infection. But even then, a flu vaccine is only effective for a few months. My PC has told me it's best to wait till mid-November, or a little later, to get a flu shot otherwise I could be vulnerable in March. That's only about 4-5 months, at best. (he also told me that it takes around 2 weeks after the shot for the anti-bodies to be at the level where I have immunity...no immediate immunity)

    anyway, that seems to dovetail with the last report about the vaccine the NIH had that was going into the 30,000 person clinical trial. That was a shot with a booster after 6 months. It might be that we could be getting a covid vaccine twice a year. Even one every 4 months would be better than getting Covid, over and over
     
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  19. wizenheimer

    wizenheimer Well-Known Member

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    Texas is doing a test run on erasing Covid cases, and reducing the positives, that you just know the white house is eager to copy:

    https://www.thedailybeast.com/texas-erases-covid-cases-and-fans-conspiracy-theory-flames?ref=home

    the right-wing universe is already using this to say Covid is fake news. Just wait until the trump zealots at HHS get a chance to massage the numbers.

    of course, what they really want is to somehow claim the mortality numbers are fake too. Funny thing is if they start removing antigen positives from the official count of positives, the mortality rate will increase
     
  20. BigGameDamian

    BigGameDamian Well-Known Member

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